Economic Evaluation Alongside Adaptive Trials webinar - 22 November

Adaptive clinical trial designs allow changes to an on-going trial based on early examinations of the data. These designs are increasing in popularity, but it is currently unclear what impact they have on health economic analyses that aim to maximise the health gained for money spent. Additionally, opportunities are potentially being missed to incorporate health economic considerations into the design and analysis of adaptive trials.

In this presentation Laura Flight, Scientific Adviser in the Science Policy and Research team at the National Institute for Health and Care Excellence (NICE), UK will provide an overview of the current use of health economics in the design and analysis of adaptive clinical trials, including the potential opportunities and barriers to this approach as highlighted by a range of stakeholders. She will describe how existing theory can be extended to the health economic context to 1) maintain an accurate economic evaluation following an adaptive trial and 2) incorporate value of information analysis at the design stage and during an adaptive design.

Who can attend:

This webinar is open to ACTA Health Economist (HEAT) SIG members and economists within member centres. If you would like information on becoming a member of the HEAT SIG please contact Michael Mihatsch at michael.mihatsch@clinicaltrialsalliance.org.au

About the presenter:

Laura Flight is a Scientific Adviser in the Science Policy and Research team at the National Institute for Health and Care Excellence (NICE), UK. Previously she worked as a Research Fellow in Health Economics and Statistics at the School of Health and Related Research (ScHARR), University of Sheffield. Laura’s methodological research to date has focussed on innovative approaches to the design and conduct of clinical trials with an emphasis on how novel statistical methods can be applied in practice.

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