SIGNet

Mission:

SIGNet’s mission is to support and facilitate Clinical Trial Network (CTN) managers in optimal establishment and ongoing management of CTN operational activities to support the delivery of high-quality clinical research.

SIGNet provides a forum for Executive Officers, Network Managers and CTN representatives to share knowledge and expertise, identify issues, exchange information, and engage in collaborative problem solving.

ACTA seeks to engage CTNs in Australia through SIGNet meetings, ACTA events, and by sharing resources and providing advice and support to newly forming or formed CTNs. In the longer term, ACTA aims to improve the efficiency and effectiveness of clinical trial network management and governance.

Purpose:

SIGNet’s convenes 2-3 times a year with the purpose to:

• Link network Executive Officers
• Facilitate information sharing and mentoring of new Executive Officers
• Provide an opportunity to share insights on activities done well and to identify solutions to problems
• Provide updates from the sector and to receive updates from ACTA.

Actions:

Development of resources including a CTN Costing table and CTN activity reports. The activity reports are filled out by SIGNet Members and circulated before each meeting to share CTN updates and challenges, which can be discussed in meetings.

Presentations in meetings on topics including ‘which business legal structure to choose? Guidance for CTNs (2022) and Teletrials, by Prof Sabe Sabesan (2022).

ACTA have developed many resources for CTNs. Some developed during the 2021-2024 Grant period include:

• Business review of Clinical Trial Networks
• Activities supporting the growth of Clinical Trial Networks in Australia
•  Fundraising strategy: guidance for CTNs
• Communications and marketing strategy: guidance for CTNs  

Current CTNs that are represented in SIGNet

Australasian College for Emergency Medicine Clinical Trials Group (ACEM)

Australasian Gastro-Intestinal Trials Group (AGITG)

Australasian Kidney Trials Network (AKTN)

Australasian Leukemia and Lymphoma Group (ALLG)

Australasian Myeloma Research Consortium (AMaRC)

Australasian Nursing and Midwifery Clinical Trials Network (ANMCTN)

Australasian Radiopharmaceutical Trials Network (ARTnet)

Australasian Society for Infectious Diseases Clinical Research Network (ASID)

Australia & New Zealand Gynaecological Oncology Group (ANZGOG)

Australia and New Zealand Intesive Care Society (ANZICS)

Australia and New Zealand Musculoskeletal Clinical Trials Group (ANZMUSC)

Australia and New Zealand Sarcoma Association Limited (ANZSA)

Australian & New Zealand Urogenital & Prostate Cancer Trials Group (ANZUP)

Australian and New Zealand Alliance for Cardiovascular Trials (ANZACT)

Australian and New Zealand Children's Haematology/Oncology Group (ANZCHOG)

Australian and New Zealand College of Anaesthetists Clinical Trials Network (ANZCA)

Australian Early Psychosis Collaboration Consortium (AEPCC) CTN

Australian Genomic Cancer Medicine Centre (AGCM)

Breast Cancer Research Centre - Western Australia (BCRC-WA)

Breast Cancer Trials (BCT)

Centre for Eye Research Australia (CERA)

Child and Youth Mental Health CTN (CYMHS)

Clinical Trials Network Australia New Zealand (CTANZ)

Clinical Trials Network Australia New Zealand (CTANZ)

Cooperative Trials Group for Neuro-Oncology (COGNO)

Growing Minds Australia Clinical Trial Network (GMA-CTN)

Icon Institute of Innovation and Research

Juvenile Diabetes Research Foundation (JDRF)

Melanoma and Skin Cancer Trials (MASC Trials)

Melanoma and Skin Cancer Trials (MASC Trials)

Mental Health Australia General Clinical Trial Network (MAGNET) 

Multiple Sclerosis Research Australia Clinical Trials Network (MSCTN)

National Endometriosis Clinical and Scientific Trials Network (NECST)

Neurodevelopment Australia

Neuroscience Trials Australia (NTA)

NSW Drug and Alcohol Clinical Research and Improvement Network (DACRIN)

Pulmonary Fibrosis Australasian Clinical Trials Network (PACT)

Palliative Care Clinical Studies Collaborative (PaCCSC)

Primary Care Collaborative Cancer Clinical Trials Group, University of Melbourne (PC4)

Psycho-oncology Co-operative Research Group (PoCoG)

Regional Trials Network - Victoria (RTN-Vic)

Thoracic Oncology Group of Australasia (TOGA)

University of Queensland Centre for Clinical Research (UQCCR)