This glossary contains definitions for terms and trial designs that are commonly encountered in the broadly defined field of ‘innovative trial designs’.
About this glossary
The intention is for this glossary to be a centralised, living document that will be updated and improved upon either suggestion or indication, with the general consensus of the ACTA Innovative Trial Design Working Group, as the field of innovative trial design grows and matures.
For the purposes of this glossary, innovative trial designs include adaptive trials that focus on either between-patient randomisation (such as multi-arm, multi-stage designs or response adaptive randomisation) or within-patient randomisation (such as sequential multiple assignment randomised trial designs), platform trials (including basket and umbrella trials), cluster randomised trials (including
stepped-wedge and cross-over trials), and embedded designs (including registry trials).
Who is it for?
Readers who may find the glossary useful include:
- human research and ethics committees
- consumers and community
- new entrants into the field of innovative trial design including students and clinical researchers
Would you like to provide feedback?
Comments, corrections, and suggested additions can be emailed directly to the ACTA Innovative Trial
Design Working Group via: acta@acta.au
Resource Documents
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