With a steady increase in the number of clinical trials comes an increasing demand for clinicians and statisticians who can serve on Data Safety Monitoring Boards (DSMB). Members of a DSMB are expected to evaluate accumulating data to monitor study conduct and participant safety and make recommendations on trial modifications including early stopping.
Presenters

Tom Snelling is a clinical scientist, Director of Health and Clinical Analytics in the School of Public Health at the University of Sydney, and an infectious diseases physician in the Sydney Children’s Hospitals Network. Tom has particular interest in vaccine preventable diseases and application of decision theory to research design. He leads a team of researchers aiming to improve healthcare and reduce the burden of infectious disease by implementing learning health systems. Tom applies Bayesian approaches to the design, implementation, and analysis of public health studies, and is successfully leading a suite of multi-institutional collaborative projects across Australia covering a range of clinical domains. These include improving treatment and prevention of severe gastroenteritis in remote Aboriginal children, primary prevention of food allergies in children, SMS text messages to improve timeliness of routine immunisation, and improving management of cystic fibrosis
Latest Resources
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ACTA Webinar – Developing a Best Practice Guide for Registry Based Trials
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STInG Chat – How to build a career as a clinical trials biostatistician
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Webinar recording: Historical and non-concurrent controls in clinical trials
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STInG Chat – ‘Securing Funding: Tips and Tricks for Investigator Grants’
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Webinar recording: Introduction to Git for Clinical Statisticians
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The processes involved in a Data and Safety Monitoring Board/Committee with special reference to the role of the various statisticians
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ACTA STInG grant advice for trial statisticians
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ACTA STInGChat – ‘Climbing the Career Cascade’
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Seamless Phase 2_3 Trials in Oncology
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Career paths for academic biostatisticians
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ACTA STInG: N-of-1 Trials Webinar Series – Webinar 2
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ACTA STInG: N-of-1 Trials Webinar Series – Webinar 1
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Effective strategies to manage data integrity risks webinar
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The Data Lifecycle: Ethical use of data webinar
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Transparency in data analyses webinar
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Webinar PIONEERing estimands in Clinical Research
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Estimands: Not just a statistical issue
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Resource for trial statisticians planning to apply for an academic promotion
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Guidance on Peer Reviewing the Statistical Aspects of a Medical Paper
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Protocols and Statistical Analysis Plans (SAPs) for Adaptive and Platform Trials
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Webinar: Estimands in Oncology – How and Why
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Seven steps for statistical success in clinical trials [Good clinical practice guidelines] Part 2
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Seven steps for statistical success in clinical trials [Good clinical practice guidelines] Part 1
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Data and Safety Monitoring Boards Webinar Series: Statistical Principles
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Data and Safety Monitoring Boards Webinar Series: How to plan well and be prepared for the unexpected
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Joint webinar on estimands in clinical trials
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Statistical Analysis Plan (SAP)
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Data Safety and Monitoring Boards (DSMB) for Adaptive Trials Webinar video
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Bayesian adaptive randomised clinical trials flyer
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ACTA STInG Notes from Members’ meeting, October 2019
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ACTA STInG 2017 Member Survey Results
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ACTA STInG Submission to the NHMRC Structural Review
Latest Events
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ACTA Webinar – Interim Data Sharing by Data Safety Monitoring Board: What to share, with whom, and why – Part 1
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ACTA Webinar – Title: The challenges of stopping trials for benefit: The lessons learnt from the immediate Kangaroo Mother Care (iKMC) trial – Part 2
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The Australian Trials Methodology Conference 2025
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Webinar: Introduction to Git for Clinical Statisticians
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ACTA STInG Trials Webinar Series: Seamless Phase 2/3 Designs in Oncology
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ACTA STInG – Stata and R Markdown Demonstrations
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ACTA STInG 3 part webinar series on Data Transparency (DT)
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Clinical Trials 2021: National Tribute and Award Ceremony
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An Introduction to Adaptive Trial Designs
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Practical approaches to Adaptive Trial Simulation
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Clarifying clinical trial aims and analysis using the estimands framework
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Seven steps for statistical success in clinical trials [Good clinical practice guidelines] Part 2
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Seven steps for statistical success in clinical trials [Good clinical practice guidelines] Part 1
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Statistical principles – Data and Safety Monitoring Boards Webinar Series
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How to plan well and be prepared for the unexpected – Data and Safety Monitoring Boards Webinar Series
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Bayesian Adaptive Randomised Clinical Trials Workshop, Sydney
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Bayesian Adaptive Randomised Clinical Trials Workshop, Melbourne
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Webinar: Data Safety and Monitoring Boards for Adaptive Trials
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Bayesian Adaptive Trials Workshops: Perth