Practical approaches to Adaptive Trial Simulation

ViCBiostat Summer School 2021, proudly supported by ACTA

Join us for an intensive workshop where you will take away the knowledge and practical skills for simulating simple adaptive trials using Monte Carlo methods. Topics include defining the inputs and outputs needed for trial simulation, and defining plausible trial scenarios for evaluation of decision quantities, thresholds and timing, Trial simulations will be generated and demonstrated using FACTS, a commercial software package, R and Stata, and graphical summaries will be used to aid communication of simulation outputs. We teach these methods focusing on a 2-arm parallel group study with adaptations based on frequentist and Bayesian methods. This workshop will be delivered over 2 half days and will cover how to generate trial simulations to support the design of a simple adaptive trial.

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