Maximise and measure the value of clinical trials to the community and the healthcare system, including the consideration of the implementation of trial results into standard care.
- Establish a community of practice involving both clinical trial networks, experts in implementation science, and end-users to grow capacity in networks to facilitate effective implementation of trial results conducted by networks
- Disseminate and promote methods to clinical trial networks to facilitate trial design that optimises capacity for implementation, to measure impact on practice, including economic impact following implementation of trial results (i.e. return-on-investment studies)
Recent group activities:
- Scope and definitions of the group were developed by leadership group early 2018
- Impact and Implementation forum held in August 2018 with national and international speakers
- A survey of all networks to establish how much they consider implementability and implementation as part of their trial designs
- A report stemming from the survey results
Current activities:
The group has recently published a pragmatic literature review and concept map in Trials journal, providing trialists with a tool to consider a range of areas in which practical action could enhance the implementability of trials. This open access article also explores how future work could validate the strength of the associations between the concepts identified and implementability of trials and investigate the effectiveness of steps to address each concept. Read the full article here.
The group is in the final stages of publishing three guidance documents for trialists. These will be published in full on the ACTA website and then condensed summaries submitted for publication in a medical journal. These documents will come under the following headings:
- Optimising for implementation
- What next after the trial?
- Measuring implementation
Future activities:
- The group is planning to present its work to the Department of Health at its next meeting with ACTA
- They will develop a tool to measure the impact of trials and training on the use of the tool
- The group hopes to evaluate key issues in the measurement of impact in trial funding proposals
Latest Resources
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Implementability Guidance Document: After The Trial
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Assessing the impact of clinical trials: a scoping literature review
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Research Prioritisation Uncovered – Workshop 2 recording
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Research Prioritisation Uncovered – Workshop 1 recording
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Understanding implementability in clinical trials: a pragmatic review and concept map
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Improving impact of clinical trials through implementability
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Implementability Super Webinar slide deck
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Implementability Super Webinar
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Guidance on Implementability
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Approaches to implementability, implementation and impact of clinical trials: a survey of Australian clinical trials networks and coordinating centres
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ANZCA CTN: Impact and Implementation
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Optimising for Implementation: IMPACT
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What clinical trialists should know about healthcare policy
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Implementation of evidence by the ANZICS Clinical Trials Group
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ALLG Clinical Trials Impact and Implementation
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Implementation: Clinical Trials
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What a trialist should know about implementation to practice
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Cochrane’s approach to implementation
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The role of AHRTCs in optimising implementation of evidence into practice and policy
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Economic evaluation of investigator-initiated clinical trials conducted by networks – Appendix: Individual trial-level results
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Strategies for supporting more trials of high value
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The Clinician Researcher’s Perspective: Measuring impact on individual clinical practice
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What we don’t know about the health and economic benefit of trials and registries in Australia
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What we know about the health and economic benefit of trials and registries in Australia
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Health system sustainability and continuous self-improvement
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The Health Service Provider’s Perspective: How should we measure impact on service delivery?
Latest News
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ACTA Teletrials Project – CTN and CC survey
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Did you miss our Research Prioritisation Uncovered workshops?
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Guidance on Implementability and Super Webinar
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Registrations open: Super webinar
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Value of Clinical Trials: Impact and Implementation Forum presentations online
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Optimising the value of clinical trials – impact and implementation forum