Controlled comparisons are a cornerstone of clinical trials. A randomised concurrent control group is the gold standard but sometimes historical or non-concurrent controls may be considered for practical or other reasons. This talk will discuss historical, non-concurrent and other types of controls in clinical trials, focusing on their definition, advantages and disadvantages.
Ian Marschner is Professor of Biostatistics at the University of Sydney and Director of Biostatistics at the NHMRC Clinical Trials Centre. He has over 30 years experience working on clinical trials and methodological research. He is a Chief Investigator for the Australian Trials Methodology (AusTriM) Research Network, and formerly he was Head of Statistics at Macquarie University, Director of Biometrics at Pfizer and Associate Professor at Harvard.
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